National Instruments/NI PXI
March 13, 2025

Understanding NI 63xx DAQ Cable and Accessory Compatibility

Reliable data acquisition starts with the right connections. Using compatible cables and accessories for your NI 63xx series DAQ devices is essential for maintaining signal integrity, ensuring precise measurements, and preventing costly hardware issues. This guide will teach you how proper compatibility safeguards your system from interference, signal degradation, and potential damage—so you can achieve accurate, dependable performance in every test and measurement application.

Since sufficient connectivity is essential to facilitate correct data transfer and system dependability, selecting the right cables and accessories will help maximize the performance of your DAQ devices. For instance, the PCIe-6323 model requires connector blocks like the SCB-68A and appropriate cables like the SHC68-68-EPM in order to function at its finest. 

In this guide, we’ll help you understand the compatibility landscape of cables and accessories for NI 63xx DAQ models.

Why Compatibility Matters

Making sure your National Instruments (NI) 63xx series DAQ devices and their corresponding cables/accessories are compatible is important, because compatibility maintains signal integrity, data accuracy, and overall system reliability. Using the correct parts assures that the signals transmitted are free from interference and degradation, leading to precise measurements and reliable performance.​

On the flip side, using incompatible cables or accessories can result in significant issues. Potential risks include signal degradation, which compromises data accuracy, and, in severe cases, physical damage to the hardware components. This can lead to increased noise, signal loss, or even short circuits, jeopardizing the entire measurement system’s functionality.​

The NI 63xx series modules offer a range of multifunction I/O capabilities such as high-speed analog inputs and outputs, digital I/O channels, and multiple counter/timers, making them most suitable for tasks such as data logging, process monitoring, and automated testing.​

Connectivity for the 63xx series is facilitated through various connector types, each serving specific purposes:​

•68-Pin VHDCI Connectors: Typically used for high-density analog and digital signal connections, these connectors support multiple channels and are designed for applications requiring compact and reliable interfaces.​

•BNC Connectors: Ideal for applications that require quick and secure connections, BNC connectors are often used for analog signal inputs and outputs, specifically in laboratory environments where frequent reconfiguration is common.​

•Screw Terminal Connectors: These provide an easy-to-use method for connecting individual wires, great for prototyping or situations where custom wiring is necessary.​

Compatibility Guide for NI 63xx Models

The NI 63xx series encompasses a variety of DAQ devices with different connectivity options. Below is a summary of compatible cables for these models:​

Compatibility Guide for NI 63xx Models

The NI 63xx series encompasses a variety of DAQ devices with different connectivity options. Below is a summary of compatible cables for these models:

1. PCIe and PXIe DAQ Devices

DAQ Device Models Compatible Cables
NI PCIe-6320, PCIe-6321, PCIe-6323, PCIe-6326, PCIe-6341, PCIe-6343, PCIe-6351, PCIe-6353, PCIe-6361, PCIe-6363, PCIe-6374, PCIe-6376, PCIe-6378 SHC68-68-EPM, SHC68-NT-S
NI PXIe-6320, PXIe-6321, PXIe-6323, PXIe-6341, PXIe-6343, PXIe-6351, PXIe-6353, PXIe-6361, PXIe-6363, PXIe-6374, PXIe-6376, PXIe-6378 SHC68-68-EPM, SHC68-NT-S

2. USB DAQ Devices

DAQ Device Models Compatible Cables
NI USB-6341, USB-6343, USB-6351, USB-6353, USB-6361, USB-6363, USB-6366 SHC68-68-EPM, SHC68-NT-S

Note: For certain models, such as the PXIe-6349, specific cable recommendations are provided to optimize performance. It’s advisable to consult the detailed specifications for each device to ensure proper cable selection.

Accessory Compatibility

Depending on your application requirements, certain accessories can improve connectivity and functionality:​

Screw Terminal Blocks: Best for applications requiring direct wire connections, such as custom setups or prototyping. They provide secure, strong  connections for analog and digital signals. Examples of screw terminal blocks include the SCB-68A and SCB-68, which are shielded connector blocks with temperature sensors. ​

BNC Connector Blocks: Best for applications that require quick and reliable connections, especially in test environments where signals are frequently connected and disconnected. The BNC-2110, for instance, offers BNC connectivity to all analog signals and some digital signals. ​

DIN Rail-Mountable Connector Blocks: Useful for industrial applications where space optimization and organization are essential. The TBX-68 is an example of a DIN rail-mountable connector block. ​

Choosing the Right Cable & Accessory for Your Application

When selecting cables and accessories, consider the signal types involved:

Analog Signals: For high-precision analog measurements, use shielded cables to minimize noise interference. Accessories like the SCB-68A shielded connector block are recommended for maintaining signal integrity. ​

Digital Signals: Unshielded cables may suffice for digital signals less susceptible to noise. However, for high-speed digital applications, shielded cables and accessories like the BNC-2110 can help prevent crosstalk and strengthen performance. 

Mixed-Signal Environments: If both analog and digital signals are involved, it’s important to separate these signals to prevent interference. Utilizing accessories that provide distinct routing for analog and digital lines, such as the BNC-2110, can help maintain signal integrity. ​

By carefully selecting compatible cables and accessories tailored to your specific signal types and application needs, you can develop accurate measurements and reliable operation of your NI 63xx series DAQ system.

​When configuring your system, it’s essential to consider data speed requirements and environmental factors for optimal performance.

Data Speed Requirements

The data transfer rate of your DAQ system significantly impacts its performance, especially in high-speed applications. Using cables and accessories that can handle the required data speeds is vital to prevent setbacks (like the NI X Series devices). ​

Environmental Factors

Environmental conditions can affect the longevity and reliability of a DAQ system. When operating in industrial settings or harsh environments, it’s important to choose accessories rated for such conditions. For example, the NI-9949 accessory is designed to operate over a wide temperature range from -40 to 70 °C, making it able to withstand industrial applications. ​

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